Pharmacodynamics of cannabinoids
نویسندگان
چکیده
منابع مشابه
Clinical Pharmacodynamics of Cannabinoids
Our knowledge of the pharmacodynamics of cannabinoids, that is, “the study of the biochemical and physiologic effects of drugs and their mechanisms of action” (The Merck Manual), has considerably increased within the past decade due to the detection of an endogenous cannabinoid system with specific receptors and their endogenous ligands. THC (D9-tetrahydrocannabinol), the main source of the pha...
متن کاملPharmacokinetics and pharmacodynamics of cannabinoids.
Delta(9)-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects caused by the consumption of cannabis, both the marijuana-like action and the medicinal benefits of the plant. However, its acid metabolite THC-COOH, the non-psychotropic cannabidiol (CBD), several cannabinoid analogues and newly discovered modulators of the endogenous cannabinoid system are also promising can...
متن کاملCannabinoids.
Since the discovery of an endogenous cannabinoid system, research into the pharmacology and therapeutic potential of cannabinoids has steadily increased. Two subtypes of G-protein coupled cannabinoid receptors, CB(1) and CB(1), have been cloned and several putative endogenous ligands (endocannabinoids) have been detected during the past 15 years. The main endocannabinoids are arachidonoyl ethan...
متن کاملAcetylcholinesterase Inhibitory Activity of Standardized Cannabinoids-rich Fractions
Background: Since cannabis has been legally allowed for medicinal purposes in many countries, it has become more interesting issue, particularly in neurologic disorders such as Alzheimer’s disease (AD). Inhibition of acetylcholinesterase (AChE) is one of the mechanisms for the treatment of AD. Objectives: The present study aimed to establish a method for preparation of cannabinoids-rich extrac...
متن کاملP 148: The Role of Cannabinoids in Ischemia Stroke
Inflammation serves a protective function in controlling infections and promoting tissue repair, and can also cause damage to tissue and disease. Many types of cells involved in this process, expressing the components of the cannabinoid signaling system that can be controlled endogenously or pharmacologically. Cannabinoids inhibit neuroinflammation and the immune cells express the whole machi...
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ژورنال
عنوان ژورنال: Archives of Pharmacy and Pharmaceutical Sciences
سال: 2019
ISSN: 2639-992X
DOI: 10.29328/journal.apps.1001013